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Can I drink with sildenafil? It is best not to drink when taking sildenafil or to drink only a small amount (one or two units). Alcohol is a depressant and tends to reduce erections and will reduce the effectiveness of treatment. Some side effects of sildenafil are likely to increase with alcohol, particularly low blood pressure.What should I do if sildenafil does not work or stops working?Sildenafil is usually effective and usually remains effective at the same dose over many years. The body does not get used to sildenafil or become immune to its effects. If there is a poor response from time to time, this is to be expected, as the circumstance around taking the tablets may not be right every time. If this happens, you should try again with the same strength tablets and can expect the same good responses as you had previously.

If your usual sildenafil repeatedly fails to help, you should consult your regular doctor to see if there has been a change in the underlying cause of your ED or to see if another type of treatment might be more suitable. See My ED medicine is not working page. Can I take sildenafil and Levitra and Cialis at the same time? No, the combination of ED tablets is potentially dangerous and can cause toxic effects of overdose. If one type of tablet does not work, its strength can be increased or an alternative type of tablet can be tried, but treatments must not be combined. Leave at least 24 hours between sildenafil and Levitra and other treatments, and 48 hours after Cialis. Can I take sildenafil with other prescription medicines? Sildenafil can be taken with most other prescription medicines, with some notable exceptions. Nitrates used mainly to treat heart disease and angina can interact and cause a dangerous fall in blood pressure. For a full list of interacting medicines check the patient information leaflet supplied with the tablets. Checks for interactions are carried out in online consolations.See also erectile dysfunction FAQs page.

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Depression and erectile dysfunction (ED) often co-occur. Phosphodiesterase type 5 inhibitors are effective in men with ED and untreated depression, or ED secondary to antidepressants. This study evaluated sildenafil treatment in Canadian men with clinically diagnosed ED (Sexual Health Inventory for Men score ≤ 21) and mild-to-moderate untreated depressive symptoms , but excluding major depressive disorder. Pretreatment screening using the Sexual Health Inventory for Men and BDI-II showed that men with ED were more likely to have depression than men without ED, and ED severity was a predictor of depression (P=0.0226). Two hundred and two men were randomized to 6 weeks of double-blind treatment with placebo (n=98) or sildenafil (n=104), initial dose of 50 mg, adjustable to 25 or 100 mg. The men were evaluated on all domains of the International Index of Erectile Function and the Sex Effects Questionnaire, Global Efficacy Questions, and Event-log data. Compared with placebo, patients treated with sildenafil had significantly greater changes from baseline in BDI-II scores (P<0.001). All International Index of Erectile Function domains and the Sex Effects Questionnaire components were also significantly improved in sildenafil group (P<0.01). The most common adverse events included headache, dyspepsia, vasodilatation, and respiratory tract infections and were generally mild in intensity.

Abstract Depression and erectile dysfunction (ED) often co-occur. Phosphodiesterase type 5 inhibitors are effective in men with ED and untreated depression, or ED secondary to antidepressants. This study evaluated sildenafil treatment in Canadian men with clinically diagnosed ED (Sexual Health Inventory for Men score ≤ 21) and mild-to-moderate untreated depressive symptoms , but excluding major depressive disorder. Pretreatment screening using the Sexual Health Inventory for Men and BDI-II showed that men with ED were more likely to have depression than men without ED, and ED severity was a predictor of depression (P=0.0226). Two hundred and two men were randomized to 6 weeks of double-blind treatment with placebo (n=98) or sildenafil (n=104), initial dose of 50 mg, adjustable to 25 or 100 mg. The men were evaluated on all domains of the International Index of Erectile Function and the Sex Effects Questionnaire, Global Efficacy Questions, and Event-log data. Compared with placebo, patients treated with sildenafil had significantly greater changes from baseline in BDI-II scores (P<0.001). All International Index of Erectile Function domains and the Sex Effects Questionnaire components were also significantly improved in sildenafil group (P<0.01). The most common adverse events included headache, dyspepsia, vasodilatation, and respiratory tract infections and were generally mild in intensity.

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Can you buy generic Viagra online? Buying brand name and generic Viagra online with Canada Drug Center is inexpensive, safe and affordable. Many Americans are choosing to buy their erectile dysfunction medications from Canada on a daily basis and they are making great savings on their medication costs. If you are still unsure, you can call us 7 days a week for more information or read some of our real customer reviews. What is Viagra? Viagra (sildenafil) is a drug used to treat male sexual function problems such as erectile dysfunction (ED). Sildenafil Citrate works, in combination with sexual stimulation, by relaxing the muscles in the blood vessels therefore increasing blood flow to the penis. This way a man can get and keep an erection. Note that erectile dysfunction drugs do not protect against sexually transmitted diseases. Practicing “safe sex” is advised. Generic Viagra is called Sildenafil and is also available for purchase. How long does Viagra last? Viagra is most effective within 30 to 60 minutes of taking but it can be taken up to four hours before sexual activity. It is most effective when taken one hour before sexual activity. Do not take more than one tablet of sildenafil within a 24 hour period. What is the cost of Viagra? The cost of your medication is based on the strength and quantity that you need. You can save up to 90% of the cost of Viagra by buying online and you can save even more by buying a 90 day supply. No Viagra coupon is needed to get our excellent prices.

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Buying brand name and generic Viagra online with Canada Drug Center is inexpensive, safe and affordable. Many Americans are choosing to buy their erectile dysfunction medications from Canada on a daily basis and they are making great savings on their medication costs. If you are still unsure, you can call us 7 days a week for more information or read some of our real customer reviews. What is Viagra? Viagra (sildenafil) is a drug used to treat male sexual function problems such as erectile dysfunction (ED). Sildenafil Citrate works, in combination with sexual stimulation, by relaxing the muscles in the blood vessels therefore increasing blood flow to the penis. This way a man can get and keep an erection. Note that erectile dysfunction drugs do not protect against sexually transmitted diseases. Practicing “safe sex” is advised. Generic Viagra is called Sildenafil and is also available for purchase. How long does Viagra last? Viagra is most effective within 30 to 60 minutes of taking but it can be taken up to four hours before sexual activity. It is most effective when taken one hour before sexual activity. Do not take more than one tablet of sildenafil within a 24 hour period. What is the cost of Viagra? The cost of your medication is based on the strength and quantity that you need. You can save up to 90% of the cost of Viagra by buying online and you can save even more by buying a 90 day supply. No Viagra coupon is needed to get our excellent prices.

Conversely, when sildenafil was used to treat erectile dysfunction in healthy elderly volunteers (65 years or over), a reduced clearance of sildenafil was observed 12,8. This reduction resulted in about 90% higher plasma concentrations of sildenafil and the active N-desmethyl metabolite compared to those seen in healthy younger volunteers (18-45 years) 12,8. Due to age-differences in plasma protein binding, the corresponding increase in free sildenafil plasma concentration was approximately 40% 12,8.